IndraLab

Statements

STAM2 binds USP8. 17 / 19
6 2 | 5 4
reach
"Hbp in turn interacts through an SH3 domain with the de-ubiquitinating enzyme UBPY [18]."
12176377
sparser
"However, it remained unclear whether the USP8–STAM complex interacts with Sec31A. Our data showed that Sec31A interacted specifically with the USP8–STAM1 complex, but not with the USP8–STAM2 complex."
29604273
sparser
"Finally, STAM2 interaction with USP8 facilitates deubiquitination of the EGFR leading to its dissociation from ESCRT-0 and engagement with ESCRT-III."
31845722
sparser
"Gab2b exhibits the canonical RxxK motif and adopts a relatively extended conformation on the surface of Grb2SH3C much in the fashion of SLP-76 and HPK1 binding to Mona/Gads SH3C ( Figures 4 A–4D) ( Ha[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
19523899
biogrid
No evidence text available
10982817
hprd
No evidence text available
10982817
biogrid
No evidence text available
20736164
reach
"Hrs might play a more direct role in releasing ubiquitin, since an Hrs binding protein interacts with the deubiquitinating enzyme UBPY."
11916981
biogrid
No evidence text available
13129930
biogrid
No evidence text available
10982817
biogrid
No evidence text available
10982817
hprd
No evidence text available
13129930
sparser
"Hrs might play a more direct role in releasing ubiquitin, since an Hrs-binding protein interacts with the deubiquitinating enzyme UBPY ( xref )."
11916981
reach
"Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR."
22841719
reach
"Finally, STAM2 interaction with USP8 facilitates deubiquitination of the EGFR leading to its dissociation from ESCRT-0 and engagement with ESCRT-III."
31845722
biogrid
No evidence text available
29604273
reach
"In addition, C-terminal portion of this P3 sequence is needed for effective binding to SH3 as in the study by Kato et al. [12], since P2 containing the N-terminal five residues of the novel sequence c[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17078930