IndraLab

Statements

USP36 activates cell population proliferation. 17 / 18
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"USP36 Promotes NB Cell Proliferation and Tumor Phenotype."
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"Multiple lines of evidence have indicated that USP36 promotes cell proliferation in a wide range of cancers through deubiquitination and stabilization of oncoproteins."
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"Functionally, elevated USP36 could promote proliferation, migration, and invasion of CRC cells in vitro and in vivo."
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"Consistently, depletion of USP36 markedly reduced the levels of tested mature miRNAs and induced overexpression of a SUMOylation-defective mutant of DGCR8 suppressed cell proliferation."
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"RBM28/p53 axis mediates USP36-induced proliferation and metastasis."
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"USP36 promotes CRC cell proliferation, migration, and invasion in vitro."
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"Our previous study clarified that ubiquitin-specific peptidase 36 (USP36) accelerates ESCC proliferation and metastasis through stabilizing YAP protein [13]."
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"As the above study revealed, USP36 promoted the cell proliferation and inhibited autophagy, while inhibiting autophagy have no impact on the cell proliferation."
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"Taken together, these results suggested that USP36 promotes proliferation and metastasis in CRC through stabilizing RBM28.Next, we evaluated whether USP36/RBM28 exerts its oncogenic effects through the p53 signaling pathway."
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"Furthermore, in GSC cells, knockout of USP36 inhibited the cell proliferation, stemness and tumorigenicity."
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"Similar to the growth deficit, we observed with ubp10Delta yeast cells, knockdown of USP36 levels reduced proliferation of HeLa cells, and deletion of scrawny reduced the proliferation of follicle and intestinal stem cells in Drosophila."
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"Overexpression of USP36 promoted NSCLC cell proliferation and inhibited NSCLC cell apoptosis."
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"Depletion of USP36 by shRNA in SK-N-BE ( 2 ) and IMR-32 resulted in a decrease in cell proliferation ( Figure 3A ) and reduced colony formation ( Figure 3B ) ."
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"Multiple studies have provided evidence that USP36 promotes the proliferation and migration of tumor cells [64]."
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"Knockdown of either Usp28 or Usp36 downregulates Myc and suppresses cancer cell proliferation in cell culture."
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"USP36 promotes proliferation and invasion of esophageal squamous cell carcinoma by deubiquitination of YAP [104]."
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"The CCK-8 assay showed that USP36 depletion suppressed cancer cell proliferation in ECA109, KYSE150, and EC9706 cells (Figs."
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