IndraLab

Statements

PMAIP1 activates KCNK18. 4 / 4
| 4
sparser
"Independent of the calcineurin pathway and independent of protein kinase A (which phosphorylates TRESK and restores baseline) is the PMA induced activation of TRESK, which occurs via protein kinase C [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
24383077
sparser
"It has been reported that human TRESK is activated by the protein kinase C (PKC) activator PMA (phorbol 12-myristate 13-acetate) in Xenopus oocytes."
30992311
sparser
"PMA activates TRESK via protein kinase C activation and demonstrates that at least part of the native regulation of TRESK is preserved in the U20S system."
24383077
sparser
"For TRESK maximal PMA activation was 1.39 ( ±0.01) fold over baseline with a pEC50 of 8.22 ( ±0.28) ( Fig. 3 )."
28882594