IndraLab

Statements

JOSD2 deubiquitinates TAFAZZIN. 3 / 3
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reach
"The tumor-promoting effects were also revealed by another study that JOSD2 deubiquitinates and stabilizes YAP/TAZ by cleaving their proteolytic ubiquitination and inhibiting the latter degradation in cholangiocarcinoma."
40240366
reach
"Recent reports have documented that TAZ can be directly deubiquitinated and stabilized by USP1 [46], USP10 [15], OTUB2 [16] and JOSD2 [47] in hepatocellular carcinoma, breast cancer and cholangiocarcinoma."
35931679
reach
"Our previous study revealed the pro-tumor function of JOSD2 in cholangiocarcinoma and found that JOSD2 deubiquitinates and stabilizes YAP/TAZ by cleaving the proteolytic ubiquitination and inhibiting the latter degradation."
38177135