IndraLab

Statements

BRCC3 decreases the amount of Cyclin. 2 / 2
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"In summary, our study indicated that BRCC36 exerts its anticalcification effect partly through β-catenin signalling.In the present study, our findings suggest that BRCC36 overexpression reduces the expression of cyclin D1, a marker of cell proliferation."
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"Additionally, western blot and RT‒PCR results demonstrated that BRCC36 overexpression downregulated the expression of the classic Wnt/β-catenin target genes c-myc and cyclin D1 at both the protein and mRNA levels (Fig. 5J, K)."
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