IndraLab

Statements

KCNH1 activates calcium(2+). 5 / 5
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"Inhibition of hEAG and IK channels induces membrane depolarization and a decrease in intracellular Ca , resulting in early G phase arrest [62]."
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"Moreover, K + channel Kv10.1 regulates serum-induced MDA-231 cells migration by enhancing calcium influx through Orai1 [18] ."
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"In our previous works, we reported that the inhibition of hEag1 channels reduces the concentration of intracellular calcium in synchronized cells in G1 phase [9]."
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"Collagen 1 elicits an increase of Kv10.1 activation that enhances basal Ca 2+ influx through Orai1, triggering ERK1/2 activation and promoting cell survival."
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"In line with this notion, Eag1 appears to modulate presynaptic Ca 2+ influx and neurotransmitter release during high-frequency neuronal firing 11."
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