IndraLab

Statements

ARNTL activates USP2. 2 / 2

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"The circadian rhythm of Usp2 is blunted in Clock mutant and Bmal1 KO mice, and the Usp2 promoter is activated by CLOCK and BMAL1, indicating that Usp2 is a direct target of these transcription factors."

25147498

➶

reach

"This suggests a scenario in USP2 -/- mice in which increased turnover of BMAL1 coincides with increased CLOCK and BMAL1 driven gene expression in the USP2 -/- SCN."

21966515

INDRA sources:

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IndraLab

Statements

ARNTL activates USP2. 2 / 2

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