IndraLab

Statements

AKT phosphorylates COPS6 on S60. 8 / 8
1 | 6 1
rlimsp
"We previously showed that S60 of CSN6 has an Akt phosphorylation site [21] and that Akt increases the steady-state expression of CSN6 [21], which in turn will be translating into E6AP stabilization."
26318036
reach
"XREF_BIBR They demonstrate that Akt directly interacts with and phosphorylates CSN6 at Ser60, which inhibits the degradation of CSN6 by reducing its ubiquitination."
23099920
signor
"Mechanistic studies show that akt causes csn6 phosphorylation at ser 60, which, in turn, reduces ubiquitin-mediated protein degradation of csn6."
23095642
reach
"XREF_BIBR Interestingly, CSN6 can be phosphorylated by Akt at Ser60, which renders CSN6 more stabilized."
23470457
reach
"S60 of CSN6 is phosphorylated by PKB/Akt 16 and is critical for CSN6 stabilization."
33101846
reach
"Mechanistic studies show that Akt causes CSN6 phosphorylation at Ser 60, which, in turn, reduces ubiquitin mediated protein degradation of CSN6."
23095642
reach
"First, we have shown that S60 of CSN6 can be phosphorylated by PKB/Akt 16 and that PKB/Akt enhances the steady‐state expression of CSN6."
33101846
reach
"19 We previously found that AKT can directly phosphorylate CSN6 at S60."
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