IndraLab

Statements

USP8 deubiquitinates MCPH1. 2 / 2

1 | 1

➶

ubibrowser

"BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1"

25733871

➶

reach

"Upon DSB induction, BRUCE promoted USP8-mediated deubiquitination of BRIT1 triggering its release and subsequent binding to γ-H2AX which is located in DSB-flanking chromatin where it facilitates chromatin relaxation."

31845722

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP8 deubiquitinates MCPH1. 2 / 2

INDRA sources:

Databases

Reading