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USP8 deubiquitinates MCPH1. 1 / 2

1 | 1

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"Upon DSB induction, BRUCE promoted USP8-mediated deubiquitination of BRIT1 triggering its release and subsequent binding to γ-H2AX which is located in DSB-flanking chromatin where it facilitates chromatin relaxation."

31845722

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USP8 deubiquitinates MCPH1. 1 / 2

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