IndraLab

Statements

ZRANB1 inhibits IL12. 2 / 2
| 2
reach
"By employing a gene targeting approach, we show that Trabid deficiency in DCs and macrophages impaired the induction of Il12 and Il23 genes without affecting the induction of many other cytokine genes."
26808229
reach
"Moreover ZRANB1 deficiency in macrophages and dendritic cells impairs the induction of IL-12 and IL-23 by the regulation of histone modifications at the IL-12 promoter, indicating a role of ZRANB1 in mediating inflammatory responses 18 and macrophage activation 19."
| PMC