IndraLab

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"For example, previous studies revealed that 4-amino-1-tert-butyl-3-(1 '-naphthyl) pyrazolo [3,4-d] pyrimidine (NA-PP1) specifically inhibits AS kinases but not their appropriate wild-type kinase because its bulkier side chain prevents NA-PP1 from accessing the ATP binding pocket of wild-type kinases [XREF_BIBR, XREF_BIBR]."