IndraLab

Statements

USP12 inhibits Neoplasm Invasiveness. 2 / 2
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"A recent study suggested that USP12 enhances the infiltration and suppressive function of M-MDSCs concomitant with PD-L1 upregulation through the deubiquitination and stabilization of NF-κB p65 [26]."
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"The absence of USP12 reduces the infiltration of mononuclear (M)-MDSCs and impairs their suppressive function, leading to enhanced CD8 + T-cell responses and reduced tumor growth [60]."
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