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"In this study, we examined intradermal siRNA permeability in the tape stripped (20 times) back skin of mice or AD like skin of auricles treated with 6-carboxyfluorescein-aminohexyl phosphoramidite (FAM)-labeled siRNA, the tight junction modulator AT1002, and the functional cytoplasm responsive stearylated peptide STR-CH2R4H2C by using confocal laser microscopy."