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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ATXN3 increases the amount of MDC1. 1 / 1

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"Our study revealed that depletion of ataxin-3 increases the levels of ubiquitylated MDC1, while at the same time reducing its residence time at DNA breaks, consistent with the idea that ubiquitylation of MDC1 is the primary signal that regulates its release from chromatin."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...