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"As compared with respective control groups, an obvious increase of IFN-alpha (XREF_FIG), IL-6 (XREF_FIG), and TNF-alpha (XREF_FIG) concentrations in poly (dA : dT)-transfected U266 cells and a significant reduction of IFN-beta (XREF_FIG), IL-6 (XREF_FIG), and TNF-alpha (XREF_FIG) secretions in T56si-2-transfected RPMI8229 cells were observed, suggesting that TRIM56 overexpression induced the production of inflammatory cytokines."