IndraLab

Statements


CYLD inhibits CARD11. 2 / 2
| 2

reach
"The K63-specific deubiquitinase Cylindromatosis (CYLD) negatively regulates CARMA1, which is required for NF-kB activation and IL-2 receptor signaling."

reach
"Interestingly, although loss of CYLD causes NF-kappaB activation in the CARMA1 deficient thymocytes, the CYLD deficiency fails to rescue the defect of CARMA1 knock-out mice in Treg development."