Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TNFAIP3 activates Neoplasm Metastasis. 3 / 3

| 2 1

➶

eidos

"Previously , our group showed that A20 promotes tumor metastasis through multi-monoubiquitylation of SNAIL1 in basal-like breast cancer ."

31449546

➶

reach

"However, when overexpressing TNFAIP3 and PLAU or upon activation of the NFkappaB pathway, all the inhibitory effects of SFE were reversed (XREF_FIG A-D), suggesting that SFE blocked the p65 promotion of TNFAIP3 and PLAU expression to inhibit ESCC cell proliferation and metastasis."

33374641

➶

eidos

"We found , through in vitro and in vivo experiments , that the A20 protein was more highly expressed in aggressive tumors and that A20 upregulation promoted metastasis ."

31449546

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...