IndraLab

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"Furthermore, tofacitinib inhibited NFkappaBp65 in PsA explants and PsAFLS, a key transcriptional factor in the inflamed joint (XREF_FIG E)."

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"XREF_BIBR In this study, tofacitinib inhibited pSTAT1, pSTAT3 and NFkappaBp65 in PsAFLS and PsA explants, an effect that was paralleled by induction of both SOCS3 and PIAS3."