IndraLab

Statements

KCNH2 activates EPHA3. 3 / 3
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"Specifically doxazosin induced apoptosis in hERG overexpressing HEK cells, but did not produce apoptosis in untransfected control cells."
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"HERG-mediated membrane currents are recorded in HEK (human embryonic kidney) 293 cells stably transfected with hERG cDNA, using the whole-cell configuration of the patch-clamp technique as previously described ."
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"After seeding on FN, herg1 mRNA expression increased in HEK–hERG1–R531C cells as it did in HEK–hERG1 cells (Fig 2A), but not in HEK–hERG1–K525C cells (Fig 5E)."
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