IndraLab

Statements

Silibinin inhibits NLRP3. 7 / 7
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"Studies reported administration of silibinin (a flavonoid complex) could reduce NLRP3 activation upon MUS stimulated monocytes."
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"Silybin inhibits the activation of the NLRP3 inflammasome in THP-1 cells by reducing the production of intracellular ROS."
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"Silibinin Downregulates the NF-kappaB Pathway and NLRP1 and NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia."
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"Therapeutic effects of silibinin on LPS induced acute lung injury by inhibiting NLRP3 and NF-kappaB signaling pathways."
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"Silymarin prevents NLRP3 inflammasome activation and protects against intracerebral hemorrhage."
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"In our study, we found that silybin inhibited endoplasmic reticulum stress and NLRP3 inflammasome activation in the livers of HFD fed mice and in cultured hepatocytes."
28970254
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"In addition, silybin inhibited the approach of calreticulin and translocase of outer membrane 20 (Tom20), prevented assembly of the NLRP3 inflammasome complex, and suppressed the accumulation of acetylated alpha-tubulin in the perinuclear region."
28970254