IndraLab

Statements

USP1 deubiquitinates TAFAZZIN. 7 / 7
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"Regarding TAZ, ubiquitin-specific peptidase 1 (USP1), ubiquitin-specific peptidase 7 (USP7), ubiquitin-specific peptidase 26 (USP26), and ubiquitin-specific peptidase 36 (USP36) deubiquitinate TAZ [37–40]."
37743467
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"Recent reports have documented that TAZ can be directly deubiquitinated and stabilized by USP1 [46], USP10 [15], OTUB2 [16] and JOSD2 [47] in hepatocellular carcinoma, breast cancer and cholangiocarcinoma."
35931679
ubibrowser
"<span class="match term0">USP1</span> Regulates <span class="match term1">TAZ</span> Protein Stability Through Ubiquitin Modifications in Breast Cancer"
33114077
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"USP1 depletion promotes the ubiquitination of TAZ and results in dysfunctional Hippo signaling pathway."
35637948
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"By deubiquitinating and stabilizing the transcriptional co-activator with PDZ-binding motif (TAZ), USP1 leads to enhanced activity of RORγt, which is an important transcription factor for T helper type 17 (Th17) cell development."
40001543
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"USP19 and USP1 promote HCC progression by deubiquitinating YAP and TAZ, respectively [ 26 , 27 ]."
38537774
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"USP1-regulated reciprocal differentiation of Th17 cells and Treg cells by deubiquitinating and stabilizing TAZ."
36600049