IndraLab

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USP19 deubiquitinates TRAF3. 3 / 4
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"USP19 suppresses cellular type I interferon signaling by deubiquitinating TRAF3, thereby promoting EV71 infection (4)."
37796126
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"Ultimately, we identified that SIAH1-mediated degradation of USP19 reversed USP19-mediated deubiquitination of MAVS, Beclin1, TRAF3, and TRIF, resulting in the activation of antiviral immune responses."
38483060
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"Deubiquitinase ubiquitin-specific protein 19 (USP19) is known to be involved in deubiquitinating Beclin1, TRAF3, and TRIF for downregulation of the type I IFN signaling."
38483060