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USP14 activates Cell Survival. 9 / 9
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"Its knockdown significantly reduced the cell survival in OSCC cells with IR treatment, while USP14 over-expression significantly promoted the cell viability in IR-treated cells, along with rescued rad[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"CCK-8 analysis suggested that USP14 knockdown markedly reduced the cell survival of OSCC cells after IR treatment ( p < 0.05 ; Fig. 2 C)."
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"The MTT assay showed that USP14 overexpression increased the cell viability in BGC-823 and MGC-803 cells, and the knockdown of USP14 repressed the cell viability in BGC-823 and MGC-803 cells."
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"In summary, USP14 promotes colorectal cancer cell proliferation and migration and enhances colorectal cancer cell viability."
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"To date, in vitro studies have shown that USP14 deficiency inhibits cell viability using MTS assay."
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"As shown in Figure XREF_FIG, pharmacological inhibition of USP14 caused dose dependent inhibition of cell viability in endometrial cancer cell lines with an IC 50 of 181.3 and 117.5 nM for HEC155 (left panel) and ECC1 (right panel), respectively."
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"Similarly, USP14 has been shown to be highly overexpressed in GBM, causing cell survival and proliferation (Figure 3) [75,80,81]."
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"Knocking down USP14 in HCC cells was reported to alter the cell cycle and induce apoptosis.Furthermore, pharmacological inhibition of USP14 using b-AP15 significantly diminished cell viability."
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"Results by CCK8 analysis in Fig. 8A and B indicated that compared with the Con group, USP14 overexpression markedly enhanced the cell viability of radioresistant KYSE-150R and TE-12R cell lines."
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