IndraLab

Statements

Sal-miR-1 activates OTUD7B. 2 / 2
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reach
"Considering that KLF4 is a transcription factor required for VSMC phenotype switching, and its stability is regulated by ubiquitination mediated protein degradation, it is reasoned that OTUD7B downregulation induced by Sal-miR-1 and 3 resulted in a decrease in KLF4 protein levels."
32685020
reach
"Results of luciferase reporter assays using OTUD7B 3 ' UTR or its mutant plasmids demonstrated that Sal-miR-1 and 3 could target the 3 ' UTR of OTUD7B mRNA and then inhibited OTUD7B expression."
32685020