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Ursolic acid inhibits RELA. 3 / 3
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"Ursolic acid also inhibited NF-kappaB-dependent reporter gene expression activated by TNF receptor (TNFR), TNFR associated death domain (TRADD), TNFR associated factor (TRAF), NF-kappaB-inducing kinase (NIK), IKK, and p65 [XREF_BIBR]."
22069560
eidos
"Ursolic acid , a triterpene presents in Prunella vulgaris L and Ilex rotunda Thunb , represses T24 bladder cancer cell growth by regulating anti-apoptotic NF-kappaB-p65 and AKT signaling , and suppressing IkappaBalpha , NF-kappaB-p65 , and AKT phosphorylation ."
33996570
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"In present study treatment with ursolic acid found to inhibit the NF-κB p50, NF-κB p65, NF-κBc-Rel, c-Fos, ATF-2 and CREB significantly ( p < 0.001) in B16F-10 melanoma cells."
18486908