IndraLab

Statements

TNFAIP3 inhibits Death. 4 / 4
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"Lee EG et al. described that TNFAIP3-deficient mice could trigger a spontaneous inflammation, cachexia, and embryonic death [ 39 ]."
33848581
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"These results indicate that TNFAIP3 expression in IEC prevents colitis involving DSS induced IEC death, but not colitis driven by T cell mediated inflammation."
22595989
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"As TNFAIP3 inhibits NF-kappaB activation and IEC death, expression of TNFAIP3 in IEC may provide an avenue to inhibit IEC NF-kappaB activation without inducing IEC death and inflammation."
22595989
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"Intestinal epithelial cell (IEC) expression of TNFAIP3 improves barrier function and tight junction integrity and prevents dextran sulfate sodium (DSS)-induced IEC death and colitis."
25234043