IndraLab

Statements


BAP1 inhibits mTORC1. 2 / 2
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eidos
"Nonetheless , the mechanisms underlying how mTORC1 is activated by BAP1 loss and whether BAP1 mutation truly imparts enhanced sensitivity to mTOR inhibition remain unclear ."

sparser
"Interestingly, there is a correlation between BAP1 inactivation and activation of mTORC1. xref , xref However, whether BAP1 loss correlates with sensitivity with mTORC1 inhibitors remains to be established."