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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BAP1 inhibits mTORC1. 2 / 2

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"Nonetheless , the mechanisms underlying how mTORC1 is activated by BAP1 loss and whether BAP1 mutation truly imparts enhanced sensitivity to mTOR inhibition remain unclear ."

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"Interestingly, there is a correlation between BAP1 inactivation and activation of mTORC1. xref , xref However, whether BAP1 loss correlates with sensitivity with mTORC1 inhibitors remains to be established."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...