IndraLab

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USP36 inhibits FBXW7. 2 / 2

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"Finally, Fbw7 activity is antagonized by the ubiquitin-specific proteases Usp28 and Usp36, which may be readily amenable to inhibition with small molecules."

26459133

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"In contrast, Fbw7-associated DUBs have the potential to antagonize ubiquitination of multiple substrates.Fbw7-mediated degradation of Myc is antagonized by Usp28 and Usp36 [99,100] ."

26459133

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IndraLab

Statements

USP36 inhibits FBXW7. 2 / 2

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