IndraLab

Statements

Protease inhibitors activates KCNH2. 3 / 3
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"Our data show that four protease inhibitors block HERG channels, suggesting that protease inhibitors could predispose individuals to QT prolongation and torsade de pointes."
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"It has been suggested that LQTs in AIDS patients is the acquired LQTs caused by the clinically used drugs, HIV protease inhibitors, because HIV protease inhibitors have been reported to block hERG K +[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Blockade of HERG channels by HIV protease inhibitors."
15721475