IndraLab

Statements



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"USP40 could interact with Claudin1 and deubiquitinates Claudin1 to stabilize its protein level."

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"The interaction between USP40 and Claudin1 was identified by immunofluorescence, co-immunoprecipitation and ubiquitination assays."

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"As a DUB, USP40 could interact with and stabilize Claudin1 in HCC."

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"Then we transfected HA-USP40 and Claudin1 plasmids into HCC cells, Co-IP findings demonstrated the interactions between USP40 and Claudin1 (Fig. 4F), which was consistent with the immunofluorescence staining results."