IndraLab

Statements

6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)-3-pyridinecarboxamide inhibits MAPK14. 6 / 6
1 1 1 | 3
sparser
"xref , xref shows that VX-702 inhibited the target kinase p38α and its closely related kinase p38β with high potency, but none of the other p38 kinases or CMGC kinases were inhibited."
28095176
dgi
No evidence text available
signor
No evidence text available
Other
sparser
"Kinase profiling data ( xref ) suggest that, at 0.5μM, VX-702 inhibits 94.7% of p38α and 77.7% of p38β activities, and 84.2% of NLK activity."
33542078
tas
No evidence text available
19950901
sparser
"As predicted, tofacitinib, kenpaullone, and VX-702 strongly inhibited their respective targets, JAK3, GSK3β, and p38α, respectively. xref xref – xref The pan–kinase inhibitor staurosporine inhibited almost all of the kinases in the panel while imatinib showed no kinase inhibition."
28095176