IndraLab

Statements

6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)-3-pyridinecarboxamide inhibits MAPK14. 3 / 7
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sparser
"Kinase profiling data ( xref ) suggest that, at 0.5μM, VX-702 inhibits 94.7% of p38α and 77.7% of p38β activities, and 84.2% of NLK activity."
33542078
sparser
"As predicted, tofacitinib, kenpaullone, and VX-702 strongly inhibited their respective targets, JAK3, GSK3β, and p38α, respectively. xref xref – xref The pan–kinase inhibitor staurosporine inhibited almost all of the kinases in the panel while imatinib showed no kinase inhibition."
28095176
sparser
"xref , xref shows that VX-702 inhibited the target kinase p38α and its closely related kinase p38β with high potency, but none of the other p38 kinases or CMGC kinases were inhibited."
28095176