IndraLab

Statements


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"Activated BRAF/MAPK pathway functions partially through USP15-mediated TBX3 stabilization, thus genetic knockout of Usp15 leads to disrupted organ development and tumorigenesis comparable to Tbx3 mutants."

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"By enhancing TGF-β signaling, USP15 promotes oncogenesis (27)."

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"USP15 stabilized TGFβ receptor I and promoted oncogenesis in glioblastoma [51]."

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"Eichhorn et al. demonstrated that USP15 stabilized TGF-β receptor I and promoted oncogenesis through the activation of TGF-β signaling (39)."

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"By enhancing TGF-beta signaling , USP15 promotes oncogenesis ( 27 ) ."