IndraLab

Statements

CACNA1H inhibits calcium(2+). 3 / 3
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"Finally, Cav3.2 and TRPV3 double KO have shown decreased fertility, altered oocyte ER Ca dynamics (fill and re-fill), and severely impaired Ca oscillations in response to fertilization (Mehregan et al., 2021)."
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"A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Ca v 3.2T-type channel activity."
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"For example, rare missense SNP mutations have been identified in the voltage dependent calcium channel gene CACNA1H (T-type Ca v 3.2), which reduce Ca v 3.2 channel activity."
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