IndraLab

Statements

Dieckol inhibits STAT1. 1 / 1

| 1

reach

"Once activated by JAK, STAT1 forms dimers with another STAT1 and translocates to the nucleus, where it binds to DNA to regulate the transcription of genes involved in the production of cytokines and chemokines.To sum up, Dieckol from E. cava reduces MDC/CCL22 production and inhibits STAT1 activation in IFN-γ-stimulated HaCaT cells, exerting anti-inflammatory effects."

39728140

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Dieckol inhibits STAT1. 1 / 1

INDRA sources:

Databases

Reading