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PI3K increases the amount of COPS6. 3 / 3
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"However, it remains uncertain whether suppression of β-TrCP by up-regulation of CSN6 facilitates Cdc25A ubiquitinated degradation and subsequently promotes cell proliferation.Recent studies have repor[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Therefore, it is important to investigate whether activation of PI3K/Akt signaling pathway increases CSN6 expression in PASMCs stimulated with PDGF."

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"Therefore, activation of PI3K/Akt signaling pathway increases the expression of CSN6 in cancer cells."