IndraLab

Statements

Celastrol decreases the amount of KCNH2. 2 / 2

| 2

reach

"Additionally, the elevated hERG1 level by miR-493 inhibitors could be partially reversed by celastrol, which is a well-known hERG channel inhibitor."

29344180

➶

reach

"Chronic exposure to celastrol potently inhibited both cardiac Kir2.1 and hERG potassium channels expression and caused QT prolongation to induce cardiotoxicity."

35656110

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Celastrol decreases the amount of KCNH2. 2 / 2

INDRA sources:

Databases

Reading