IndraLab

Statements

OTUD7B binds OTUD7A. 9 / 9
2 | 1 6
sparser
"Interestingly, a recent study showed that OTUD7A and OTUD7B interact with and modify Lys11/Lys63 heterotypic chains in order to regulate DNA damage [ xref ]."
36604605
sparser
"In addition, Cezanne2 interacts with Cezanne ( xref D), and the DUB activity of Cezanne2 is important for its function ( xref B)."
31699778
sparser
"Thus, Cezanne and Cezanne2 likely form a complex, with both of the DUB activities required for promoting recruitment of DNA repair factors."
31699778
sparser
"Increased Lys11-linkage ubiquitination due to lack of Cezanne DUB activity compromises the recruitment of Rap80/BRCA1-A. Cezanne2 interacts with Cezanne, facilitating Cezanne in the recruitment of Rap80/BRCA1-A, Rad18, and 53BP1, in cellular resistance to ionizing radiation and DNA repair."
31699778
biogrid
No evidence text available
31699778
sparser
"Cezanne2 interacts with Cezanne, playing a facilitating role in Rap80/Abraxas/BRCA1, Rad18, and 53BP1 recruitment, DNA repair, and cellular resistance to IR."
31699778
biogrid
No evidence text available
33961781
reach
"Thus, it is likely that Cezanne and Cezanne2 form a complex and that the DUB activity of both of these two proteins is required for promoting Rap80/Abraxas/BRCA1, Rad18, and 53BP1 recruitment.Due to the role of Cezanne and Cezanne2 in the recruitment of the Rap80/BRCA1-A complex, Rad18, and 53BP1, we examined their roles in DNA damage repair and cellular resistance to IR."
31699778
sparser
"Cezanne2 interacts with Cezanne, promoting recruitment of Rap80/Abraxas and 53BP1 and DNA repair."
31699778