IndraLab

Statements



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"Those initial findings were followed by a series of seminal studies that demonstrated that integrin-mediated cell adhesion of KCNH2 promotes cell differentiation."

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"KCNH2 affected the process in vivo (Fig. 2B and C) and has been found to mediate the differentiation of rESCs into cardiomyocytes in vitro (13), but the mechanism underlying the arrest of embryonic development in the absence of KCNH2 is unclear."

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"The hERG potassium channel blockage by a new 36-residue scorpion toxin BmKKx2, a potent hERG channel blocker with IC 50 of 6.7 +/-1.7 nM, enhanced the erythroid differentiation of K562 cells."

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"Here, we show that differentiation of hESCs into embryonic ECs is driven by the expression of ETV2, ERG1 and FLI1."