IndraLab
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"In our current study, TRAF6 and phosphorylated AKT expression were repressed after OTUB2 knockdown, which suggested that AKT signaling might be associated with the regulation of cell proliferation and migration mediated by OTUB2 in TNBC.The approval of bortezomib for treating multiple myeloma has confirmed the proteasomes as a valid target for anti-cancer therapy [49]."