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TNF binds INSR and IRS1. 1 / 1

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"TNF effect on IRS-1 in Fao hepatoma cells was not associated with a significant reduction in insulin receptor tyrosine kinase activity as measured in vitro but impaired the association of IRS-1 with phosphatidylinositol 3-kinase, localizing TNF impact to IRS-1."

7559552

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Statements

TNF binds INSR and IRS1. 1 / 1

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