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BRCC3 deubiquitinates lipopolysaccharide. 2 / 2

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"NLRP3 is rapidly deubiquitylated by BRCC3 upon exposure of cells to LPS and this is required for its full activation [ 46 • ,47 • ]."

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"Recently, BRCC3 in the cytosol has been reported to promote the inflammasome activation by deubiquitinating NLRP3 in LPS primed macrophages [XREF_BIBR]."

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BRCC3 deubiquitinates lipopolysaccharide. 2 / 2

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