IndraLab

Statements


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"Propofol pretreatment also prevented the association of NLRP3, ASC and pro-caspase-1 in LPS injured cardiomyocytes."

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"The results indicated that propofol pretreatment suppressed the priming and activation of NLRP3 inflammasome in LPS injured cardiomyocytes."

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"The results suggested that propofol pretreatment inactivated HMGB1 dependent NLRP3 inflammasome signaling, which involved PPARgamma activation."

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"Propofol up-regulated Nrf2 and down-regulated NLRP3 in VILI model."

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"In the rat model, propofol reduced CFA-induced inflammatory pain and inhibited the inflammatory response by regulating the p38MAPK-NF-κB pathway and the NLRP3 inflammasome."

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"Propofol Inhibits NLRP3 Inflammasome and Attenuates Blast Induced Traumatic Brain Injury in Rats."

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"Propofol significantly inhibits BK induced increase of NLRP3 inflammasome."

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"Therefore, the results suggested that the potential beneficial effects of propofol against septic myocardial injury were dependent on PPARgamma activation to suppress HMGB1 dependent NLRP3 inflammasome activation."