IndraLab

Statements


Pan ubiquitinates OTUD5. 2 / 2
| 2

sparser
"Therefore, we verified cooperative actions of TRIP12 and UBR5 in OTUD5 pan-ubiquitylation using TUBE2."

sparser
"Using TUBE2 (tandem ubiquitin-binding entity 2), which serves as a pan-ubiquitin chain binder when four repeats of the UBA1 domains from HR23A are tandemly fused xref , we found that OTUD5 pan-ubiquitylation was enhanced by the expression of wild-type, but not catalytically inactive (C1959A), TRIP12 (Fig.  xref )."