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TNFAIP3 inhibits IL1. 2 / 3

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"A20 also inhibits TNF and IL-1 induced activation of NF-κB, suggesting that it may act as a general inhibitor of NF-κB activation xref – xref ."

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"TNFaIP3 prevents the NFκB-dependent upregulation of NLRP3 and conversion of pro-IL1β to mature IL1β through the binding of its A20-like zinc finger domain to ubiquitin chains [52]."

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IndraLab

Statements

TNFAIP3 inhibits IL1. 2 / 3

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