IndraLab

Statements

SCN2A inhibits sodium(1+). 2 / 2

| 2

reach

"Here, the complete loss of Scn2a led to an increase in Na 1.6 axon initial segment staining and persistent sodium current, similar to previous work showing Na 1.2 compensation for loss of Na 1.6."

35233206

➶

reach

"Lower levels of SCN1A, SCN2A, SCN3A, SCN4A and SCN8A expression have also been reported in heart and shown to contribute approximately 23% of the total functional sodium channels in mouse ventricular myocytes and 27% in human atrial myocytes, based on TTX sensitivity."

27702655

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

SCN2A inhibits sodium(1+). 2 / 2

INDRA sources:

Databases

Reading