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Statements

USP18 binds MIB2. 3 / 3
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sparser
"Immunoprecipitation assay demonstrated that USP18 could interact with MIB2 (Fig. xref A and B and Fig. xref E)."
38779488
reach
"To investigate whether USP18 and MIB2 could directly promote the degradation of GSDMD-N, we examined whether the GSDMD I104N mutant altered the binding of USP18/MIB2 to GSDMD and whether its degradation was mediated by USP18/MIB2, ensuring the accuracy of subsequent experiments."
38779488
reach
"We observed that the interaction between GSDMD and USP18/MIB2 showed no difference in WT GSDMD and I104N GSDMD-transfected cells (Fig. S6D and E)."
38779488