IndraLab

Statements

USP25 activates CTNNB1. 7 / 7
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"Consistently, knockdown of USP25 also blocked Wnt3a-induced accumulation of β-catenin in HEK293T cells (Fig. 5C)."
28619731
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"Amplification of USP21 deubiquitinase promotes pancreatic cancer cell growth and stemness via Wnt and beta-catenin signaling [XREF_BIBR]."
33291655
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"Nuclear USP21 activates Wnt/beta-catenin pathway and promotes cancer cell stemness."
31488580
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"USP25 promotes HCC growth by activating the Wnt/beta-catenin signaling pathway ."
37439386
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"This suggests that USP25 acts as a DUB of tankyrase to stabilize tankyrase and induce a positive process of Wnt and beta-catenin signaling [XREF_BIBR]."
32486158
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"USP21 activates Wnt/beta-Catenin signaling to accelerate ESCC progression in a G3BP1-dependent manner."
38906857
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"USP25 modulates the Wnt/beta-catenin pathway through tankyrases."
28619731