IndraLab

Statements


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"Glatiramer acetate (GA), a FDA approved treatment for MS, was shown to promote activation of anti-inflammatory monocytes by reducing STAT1 signaling."

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"These results suggest that GA could inhibit the activations of STAT1 and -3 in PBMCs, in addition to brain resident immune cells."

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"GA attenuates the STAT1 and -3 signaling in peripheral blood mononuclear cells, but not neuronal cells."

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"These results indicate that the ability of GA to inhibit the activations of STAT1 and -3 is not mediated through IFNgamma -/- or IFNgammaR -/- system."