IndraLab

Statements

CALM1 binds CP. 5 / 5
| 5
sparser
"While Cp183 were largely spherical at a Cp:CAM 1:1 molar ratio, they were heavily deformed or even disassembled when DTT was present, similar to the effect observed on Cp149 + CAM-A in absence of DTT (Fig.  xref )."
36709212
sparser
"For a deep analysis of CAM interaction with Cp at the dimer–dimer interface and the optimal prediction of Cp mutations that confer resistance to CAMs, we analyzed CAM interaction with Cp in the context of capsids or CpY132A hexamer from the structures deposited in the database in detail."
40143261
sparser
"In the Y132A mutant, each of the three dimer-dimer interfaces in the hexamer accommodates one CAM (Fig.  xref ), while in the Cp150 capsid, only one CAM binds per dimer in the B and C subunits (Fig.  xref ); how this relates to CAM binding to wild-type Cp remains to be determined, because as the aberrant, irregular assemblies observed upon addition of CAM-A to wild-type Cp149 and alike have not been investigated by any direct structural approaches."
36709212
sparser
"Such data underscore how the specific CAM-Cp contacts can differentially affect morphological phenotypes, including the hexagonal sheet or tube structures seen with some CAM-A compounds [ xref , xref ]."
| PMC
sparser
"Biophysical/Structural Characterization of HBV Cp-CAM Interactions."
| PMC