IndraLab

Statements


FFA activates KCNMA1. 2 / 2
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"In GH 3, BK channel activation by FFA requires a FA with at least one double bond, and a significant correlation was described between the degree of cis unsaturation and the extent of channel activation."

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"Further structural features of FFA required to increase BK channel activity have been defined : FFA must have a negatively charged head group and a sufficiently long (C> 8) carbon chain."